Chronic Cholecystitis: Complication and Prognosis

Chronic inflammation of the gallbladder creates a very favorable environment for the formation of the gallstones. Most of the complications associated with chronic cholecystitis are directly caused by gallstones.

• Pancreatitis – gallstones that appear within gallbladder as a result of constant inflammation and changes to the composition of the bile can sometimes get lodged just before or within the sphincter of Oddi. This can lead to acute or chronic pancreatitis, since the pancreatic enzymes are unable to leave the pancreas.
• Jaundice – gallstones that get stuck in the common bile duct prevent the free flow of bile and caused it to get reabsorbed into the bloodstream. This causes a rise in direct bilirubin, causing the skin to have a yellowing tint.
• Cancer of the gallbladder – is has been noted that 80% of the patients with cancer of the gallbladder have gallstones, created as a result of chronic cholecystitis. This most probable explanation is that gallstones constantly irritate the walls of the gallbladder. At first this causes metaplasia, which then transforms into cancer.

Prognosis

Prognosis for people with chronic cholecystitis is good if the patient diligently follows the diet and does everything prescribed by the doctor. This prevents the formation of gallstones (which are the main culprits behind all the complications) and greatly improves the quality of life of the patient.